3 Many side effects are transient, but the frequency of these events is not specified May 7, 2021 · Individuals with these conditions may experience a sunburn, painful blistering, and changes to skin color while taking Plaquenil
Very rare (less than 0
See more The reported hematological side effects of hydroxychloroquine include aplastic anemia, agranulocytosis, thrombocytopenia, and hemolytic anemia in
A detailed literature search uncovered only a few past case reports detailing this particular side effect with hydroxychloroquine, and none gave the incidence for
frequent infections with a high temperature, sore throat or mouth ulcers
Key Messages Hydroxychloroquine is associated with several rare but serious adverse reactions that may warrant immediate discontinuation of the medicine
Nausea, vomiting, and diarrhea are the most common side effects of hydroxychloroquine (Plaquenil)
Hydroxychloroquine side effects Get emergency medical help if you have signs of an allergic reaction to hydroxychloroquine ( hives , difficult breathing, swelling
abdominal pain
Hemat: AGRANULOCYTOSIS, APLASTIC ANEMIA, leukopenia, thrombocytopenia
uncontrolled eye movements
Adverse hematologic effects including neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia have been rarely associated with 4-aminoquinolines
It was first used to treat malaria
muscle weakness, cramps, stiffness or spasms, or changes in how your skin feels such Aplastic Anemia ; Thrombocytopenic Disorder your doctor may instruct you to lower your dose until you find the dose that works best with the fewest side effects take hydroxychloroquine at Abstract
Tell patient to take hydroxychloroquine exactly as prescribed because taking too much may cause serious adverse reactions and taking too little or skipping doses decreases effectiveness
Toxic chemicals, such as some used in pesticides and insecticides, and benzene, an ingredient in gasoline, have been linked to aplastic anemia
Antibiotics help treat infections
Monitor blood cell counts periodically in patients on prolonged hydroxychloroquine sulfate therapy
Maintenance dose: 200 to 400 mg salt (155 to 310 mg base)/day orally divided in 1 or 2 doses
sudden, severe weakness or numbness in the arm or leg
Plaquenil can decrease levels of certain blood Plaquenil is approved to treat RA in adults
Side effect risk may increase with higher doses and long-term treatment
Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda
menstrual problem
Pharmacokinetics: Following a single 200 mg oral dose of PLAQUENIL to healthy male volunteers, the mean peak blood concentration of hydroxychloroquine was 129
a persistent headache