Drug Plavix is a P2Y12 platelet inhibitor indicated for: Acute coronary syndrome
The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown
Clopidogrel side effects Adults—At first, 300 milligrams (mg) taken as a single dose
1) Medscape - Indication-specific dosing for Plavix (clopidogrel), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information
Clopidogrel is in a class of medications called antiplatelet medications
Uses Warnings Before taking Dosage Side effects Interactions FAQ What is Plavix? Includes Clopidogrel indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more
In patients who need an antiplatelet effect within hours, initiate Plavix with a single 300 mg oral loading dose and then continue at 75 mg once daily
About clopidogrel Clopidogrel is an antiplatelet medicine
Adult: In the management of acute ST-elevation MI: In combination with aspirin (with or without thrombolytics): ≤75 years 300 mg loading dose, followed by 75 mg once daily
Plavix is available in generic form
As continuation therapy in patients with acute coronary syndrome already initiated with separate clopidogrel and Maintenance Dose; Oral antiplatelet agents: Aspirin: Loading dose of 162-325 mg orally 11 Aspirin may be chewed to achieve faster action: Maintenance dose of 75-100 mg orally daily 24,25: Clopidogrel: Loading dose of 600 mg orally 19 A lower loading dose of 300 mg should be considered in patients after fibrinolytic therapy 5: Maintenance dose Side Effects
A 75mg oral dose of clopidogrel is 50% absorbed from the intestine
For patients with non-ST-segment elevation ACS (unstable angina [UA]/non-ST-elevation myocardial infarction [NSTEMI]), Plavix has been shown to reduce the rate of myocardial infarction (MI) and stroke
Plavix Indications
(clopidogrel, prasugrel, or ticagrelor) for dual antiplatelet therapy (DAPT) after PCI or ACS P2Y12 inhibitor) is included
Rifampicin — metabolism of clopidogrel to its active metabolite is induced slightly increasing antiplatelet effect
Click to view Clovixa detailed prescribing information
Side effects of clopidogrel
Use with loading dose of aspirin (300-325 mg) and daily maintenance dose of 75-100 mg
Elimination Following an oral dose of 14 C-labeled clopidogrel in humans, approximately 50% of total radioactivity was excreted in urine and approximately 46% in feces over the 5 days post dosing
The same guidelines asserted that, currently, insufficient INDICATIONS AND CLINICAL USE MI, Stroke or Established Peripheral Arterial Disease CLOPIDOGREL (clopidogrel bisulfate) is indicated for the secondary prevention of Use of CLOPIDOGREL combined with low-dose ASA in patients with Atrial Fibrillation, who are considered unsuitable for anticoagulation therapy Key Points for Practice
Apixaban - The dose of apixaban is 5 mg twice daily (approximately 12 hours apart) unless the patient has two or more of the following: age ≥80 years, body weight ≤60 kg, or serum creatinine level ≥1
SIDE EFFECTS: See also Precautions section
Over time, numerous antiplatelet agents have been developed with a multitude of indications
The recommended daily dose of Plavix is 75 mg once daily orally, with or without food [see Clinical Pharmacology (12
CYP2C19 poor metabolizer status is associated with diminished antiplatelet response to clopidogrel
11 Summarizing the data on more than 25,000 patients from both randomized and Most importantly, the trial was limited by the use of low-dose aspirin Clopidogrel is a new antiplatelet drug similar to ticlopidine
(See "Antiulcer medications: Mechanism of action, pharmacology, and side effects"
Clopidogrel Class and Category
Clopidogrel only comes in the form of a tablet you take by mouth
Tablets: 75 mg, 300 mg (3) ---------------------------CONTRAINDICATIONS---------------------------------- Active pathological bleeding, such as peptic ulcer or intracranial hemorrhage Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack ), recent stroke, or blood circulation disease (peripheral Drug details
It keeps platelets in your blood from coming together and making clots
If you have certain heart conditions, your doctor might suggest Plavix as a treatment option for you
What Is Plavix? Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of
View clopidogrel information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding and contra-indications
Plavix is a P2Y12 platelet inhibitor indicated for: Acute coronary syndrome
Clopidogrel may also increase the chance of serious bleeding in some people
Clopidogrel is an antiplatelet medicine
Clopidogrel 75 mg and aspirin 100 mg tab
Rifampicin — metabolism of clopidogrel to its active metabolite is induced slightly increasing antiplatelet effect
223
9 The active metabolite of clopidogrel reaches a maximum concentration after 30-60 minutes
Initiating Plavix without a loading dose will delay establishment of an antiplatelet effect by several days [see Clinical Pharmacology (12
Most of the Includes Clopidogrel indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more
Certain conditions such as heart disease can predispose a dog or cat to blood clots, and these blood clots can lead to other problems such as paralysis, lung injury, or brain injury (stroke)
S
Plavix is a prescription drug used to reduce the risk of heart attack and stroke in adults who: * For this use, Plavix is taken with aspirin
5
Postmarketing side effects of clopidogrel reported include: Blood and lymphatic system disorders: Agranulocytosis, aplastic anemia / pancytopenia, thrombotic thrombocytopenic purpura ( TTP ), acquired hemophilia A
Examples include bruising, bleeding, and PLAVIX prescription and dosage sizes information for physicians and healthcare professionals