DMI is soluble in many ingredients including water, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20, and polysorbate 80; It is insoluble in Dimethyl Isosorbide
Isosorbide dimethyl has a low level of toxicity and is referred to as a green solvent due to its production from renewable/raw material
Ethanol, dimethyl sulfoxide, dimethyl isosorbide, isopropyl myristate and propylene glycol were investigated as chemical penetration enhancers
Physical state: Liquid
Average mass 174
Dimethyl isosorbide is mainly used as a solvent because it is not only water-soluble but also soluble in some of the organic solvents and oils
The results below support the claim that Dimethyl Isosorbide (Arlasolve DMI) enhances delivery into the epidermis but does not promote the product into the Granactive Retinoid (Dimethyl Isosorbide (and) Hydroxypinacolone Retinoate-Grant Industries) – claimed to be less irritating than Retinol and effective without needing to be metabolized to Retinoic acid; k3 Retino-A (Retinyl Retinoate -Ultra Chemical) - claimed to be more photo and heat stable than Retinol
Dimethyl isosorbide ~98% (GC); EC Number: 226-159-8; Synonyms: Isosorbide dimethyl ether; find Sigma-Aldrich-D7669 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich